I sent her your email address.. Id hate to see her go threw what you did.
Heres a few of replys, Theres about 70!
"university of minnesota has alot of current info. very helpful people. i manage my guy with low starch pellets, therapeutic vit E (10k IU) daily, and no longer event. if i cannot work him, his feed gets cut in half. very manageable with guidance from vet/feed nutritionists. good luck."
"My old barrel mare was diagnosed with this. I changed her feed to a high fat/fiber low stach/carb diet and no alfalfa, lots of turnout (24/7) and she never had another problem. I also give her electrolytes before and after I ran her. I fed Triple Crown Complete. I loved it so much I switched all my horses over to it and still feed it today...5 years later. Good luck and it is manageable!"
"I completely agree with redduns diet. We took this mare off sweet feed and good grass hay and she never had another episode."
"my two year old was diagnosed with this last year. We swapped her to Ultimatum ( low starch feed by Purina) . She lives in a stall and gets some turnout. We do exercise her everyday. If we miss a large time frame working her , we make sure we get her back in shape before hard exercise. So far she is doing GREAT !!!! She only had the one episode ) that lead the testing.. no more. We swapped her feed and changed her to regular exercise seemed to work great for her !!
There are MANY MANY horses with this .. these horses can and do return to a very normal life even as a serious competing horse"
From what I understand there are 3 bloodlines associated with this condition. Do you know what they are? For some reason the bloodlines have not been published.Did you know of this comment Bluejay??????http://www.addl.purdue.edu/newsletters/2000/summer/eer.shtmlWe describe a gain of function mutation in the skeletal muscle glycogen synthase gene that is responsible for a novel myopathy, and is highly prevalent in multiple breeds of horses because it arose before the founding of many modern breeds.
Polysaccharide Storage Myopathy (PSSM) is a novel glycogenosis in horses characterized by abnormal glycogen accumulation in skeletal muscle and muscle damage with exertion. It is unlike glycogen storage diseases resulting from known defects in glycogenolysis, glycolysis and glycogen synthesis that have been described in humans and domestic animals. A genome wide association identified GYS1, encoding skeletal muscle glycogen synthase (GS), as a candidate gene for PSSM. DNA sequence analysis revealed a mutation resulting in an arginine to histidine substitution in a highly conserved region of GS. Functional analysis demonstrated an elevated GS activity in PSSM horses and haplotype analysis and allele age estimation demonstrated that this mutation is identical by descent among horse breeds. This is the first report of a gain of function mutation in GYS1 resulting in a glycogenosis.
Keywords: Genome-wide association, horse, glycogen storage disease, glycogen synthase, gain-of-function mutation, polysaccharide storage myopathy
Unfortunately it can happen in many more breeds than that. It is most prevelent in Draft horses, but has been seen in ponies, Walkers & even mules. Most times it is misdiagnosed & too many people are not willing to have a muscle biopsy to confirm or disprove it.
According to Molly McCue at the Univ. of MN, she told me in an email that "Some DVMs recommend a “pound of fat per day” (2 cups) but based on our research, it is not necessary to provide that much fat, as long as the diet is low in starch and the horse is getting enough fat to meet his energy requirements." According to their website, PSSM horses need about 15-20% of their digestible energy as fat. They also recommend feeding Ultium right there on their web site.
The Ultium provides 12.4% and the cup of oil per day provides more than enough to meet the recommended 15-20%.
We don't work our horse very hard, so if we did, we would feed more corn oil. We only ride about an hour at a time, 3-5x per week.
I did try feeding cocosoya as well as corn oil. There was no difference in palatability
Anyway, I know this is long, But Bluejay, I thought you may be interested in some of this information, More than likely you have seen this, been told this but I thought you might find it interesting.